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Barriers to genome editing with CRISPR in bacteria

Genome editing is essential for probing genotype-phenotype relationships and for enhancing chemical production and phenotypic robustness in industrial bacteria. Currently, the most popular tools for genome editing couple recombineering with DNA cleavage by the CRISPR nuclease Cas9 from Streptococcus...

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Bibliografiske detaljer
Udgivet i:J Ind Microbiol Biotechnol
Main Authors: Vento, Justin M., Crook, Nathan, Beisel, Chase L.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301779/
https://ncbi.nlm.nih.gov/pubmed/31165970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-019-02195-1
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