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MicroRNA-182-5p protects human lens epithelial cells against oxidative stress-induced apoptosis by inhibiting NOX4 and p38 MAPK signalling

BACKGROUND: MicroRNAs (miRNAs) are abnormally expressed in various ocular diseases, including age-related cataract. However, the role of miR-182-5p in the progression of age-related cataract remains unclear. METHODS: The expression of miR-182-5p in HLE-B3 cells was detected by qRT-PCR. HLE-B3 cells...

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Detalhes bibliográficos
Publicado no:BMC Ophthalmol
Main Authors: Li, Zhao-Na, Ge, Ming-Xu, Yuan, Zhong-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301500/
https://ncbi.nlm.nih.gov/pubmed/32552665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-020-01489-8
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