Bone protection by inhibition of microRNA-182

Targeting microRNAs recently shows significant therapeutic promise; however, such progress is underdeveloped in treatment of skeletal diseases with osteolysis, such as osteoporosis and rheumatoid arthritis (RA). Here, we identified miR-182 as a key osteoclastogenic regulator in bone homeostasis and...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Inoue, Kazuki, Deng, Zhonghao, Chen, Yufan, Giannopoulou, Eugenia, Xu, Ren, Gong, Shiaoching, Greenblatt, Matthew B., Mangala, Lingegowda S., Lopez-Berestein, Gabriel, Kirsch, David G., Sood, Anil K., Zhao, Liang, Zhao, Baohong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173760/
https://ncbi.nlm.nih.gov/pubmed/30291236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06446-0
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