Overexpression of Cytochrome P450 2A6 in Adrenocortical Carcinoma

BACKGROUND: Cytochrome P450 (CYP) mediated metabolism of chemotherapeutic agents contributes to chemotherapy resistance in multiple malignancies. Adrenocortical carcinoma (ACC) is known to have a poor response to adjuvant therapies; however, the mechanism remains unknown. Recent comprehensive geneti...

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Publicado en:Surgery
Main Authors: Murtha, Timothy D., Brown, Taylor C., Rubinstein, Jill C., Haglund, Felix, Juhlin, C. Christofer, Larsson, Catharina, Korah, Reju, Carling, Tobias
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301492/
https://ncbi.nlm.nih.gov/pubmed/28073588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2016.11.036
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