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Membrane anchoring of Hck kinase via the intrinsically disordered SH4-U and lengthscale associated with subcellular localization

Src family kinases (SFKs) are a group of non-receptor tyrosine kinases that are characterized by their involvement in critical signal transduction pathways. SFKs are often found attached to membranes but little is known about the conformation of the protein in this environment. Here, solution nuclea...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Pond, Matthew P., Eells, Rebecca, Treece, Bradley W., Heinrich, Frank, Lösche, Mathias, Roux, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301414/
https://ncbi.nlm.nih.gov/pubmed/31877324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.11.024
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