Bioengineered airway epithelial grafts with mucociliary function based on collagen IV- and laminin-containing extracellular matrix scaffolds

Current methods to replace damaged upper airway epithelium with exogenous cells are limited. Existing strategies use grafts that lack mucociliary function, leading to infection and the retention of secretions and keratin debris. Strategies that regenerate airway epithelium with mucociliary function...

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Vydáno v:Eur Respir J
Hlavní autoři: Hamilton, Nick J.I., Lee, Dani Do Hyang, Gowers, Kate H.C., Butler, Colin R., Maughan, Elizabeth F., Jevans, Benjamin, Orr, Jessica C., McCann, Conor J., Burns, Alan J., MacNeil, Sheila, Birchall, Martin A., O'Callaghan, Christopher, Hynds, Robert E., Janes, Sam M.
Médium: Artigo
Jazyk:Inglês
Vydáno: European Respiratory Society 2020
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301290/
https://ncbi.nlm.nih.gov/pubmed/32444408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.01200-2019
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