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Bioengineered airway epithelial grafts with mucociliary function based on collagen IV- and laminin-containing extracellular matrix scaffolds

Current methods to replace damaged upper airway epithelium with exogenous cells are limited. Existing strategies use grafts that lack mucociliary function, leading to infection and the retention of secretions and keratin debris. Strategies that regenerate airway epithelium with mucociliary function...

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Dades bibliogràfiques
Publicat a:Eur Respir J
Autors principals: Hamilton, Nick J.I., Lee, Dani Do Hyang, Gowers, Kate H.C., Butler, Colin R., Maughan, Elizabeth F., Jevans, Benjamin, Orr, Jessica C., McCann, Conor J., Burns, Alan J., MacNeil, Sheila, Birchall, Martin A., O'Callaghan, Christopher, Hynds, Robert E., Janes, Sam M.
Format: Artigo
Idioma:Inglês
Publicat: European Respiratory Society 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301290/
https://ncbi.nlm.nih.gov/pubmed/32444408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.01200-2019
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