Bioengineered airway epithelial grafts with mucociliary function based on collagen IV- and laminin-containing extracellular matrix scaffolds

Current methods to replace damaged upper airway epithelium with exogenous cells are limited. Existing strategies use grafts that lack mucociliary function, leading to infection and the retention of secretions and keratin debris. Strategies that regenerate airway epithelium with mucociliary function...

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Detalhes bibliográficos
Publicado no:Eur Respir J
Main Authors: Hamilton, Nick J.I., Lee, Dani Do Hyang, Gowers, Kate H.C., Butler, Colin R., Maughan, Elizabeth F., Jevans, Benjamin, Orr, Jessica C., McCann, Conor J., Burns, Alan J., MacNeil, Sheila, Birchall, Martin A., O'Callaghan, Christopher, Hynds, Robert E., Janes, Sam M.
Formato: Artigo
Idioma:Inglês
Publicado em: European Respiratory Society 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301290/
https://ncbi.nlm.nih.gov/pubmed/32444408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.01200-2019
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