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Bcl‐2/Bcl‐xl inhibitor APG‐1252‐M1 is a promising therapeutic strategy for gastric carcinoma

Gastric carcinoma is the third major cause of cancer‐related death in China. Bcl‐2 and other BH3 family proteins are critically important in the process of apoptosis pathway, which may be a promising target. APG‐1252‐M1 specifically connects to Bcl‐2 and Bcl‐xl. The antitumor effect of APG‐1252‐M1 i...

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Publicado en:Cancer Med
Autores principales: Yi, Hanjie, Qiu, Miao‐Zhen, Yuan, Luping, Luo, Qiuyun, Pan, Wentao, Zhou, Suna, Zhang, Lin, Yan, Xianglei, Yang, Da‐Jun
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7300393/
https://ncbi.nlm.nih.gov/pubmed/32346976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3090
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