In vivo characterization of [(18)F]AVT-011 as a radiotracer for PET imaging of multidrug resistance

PURPOSE: Multidrug resistance (MDR) impedes cancer treatment. Two efflux transporters from the ATP-binding cassette (ABC) family, ABCB1 and ABCG2, may contribute to MDR by restricting the entry of therapeutic drugs into tumor cells. Although a higher expression of these transporters has been correla...

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Détails bibliographiques
Publié dans:Eur J Nucl Med Mol Imaging
Auteurs principaux: Kannan, Pavitra, Füredi, András, Dizdarevic, Sabina, Wanek, Thomas, Mairinger, Severin, Collins, Jeffrey, Falls, Theresa, van Dam, R. Michael, Maheshwari, Divya, Lee, Jason T., Szakács, Gergely, Langer, Oliver
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2019
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299908/
https://ncbi.nlm.nih.gov/pubmed/31729540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-019-04589-w
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