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COVID-19 and pneumonia: a role for the uPA/uPAR system

Here, we highlight recent findings on the urokinase plasminogen activator (uPA)/uPA receptor (uPAR) system that suggest its potential role as a main orchestrator of fatal progression to pulmonary, kidney, and heart failure in patients with coronavirus. Patients with prolonged background inflammation...

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Bibliografiske detaljer
Udgivet i:Drug Discov Today
Main Authors: D’Alonzo, Daniele, De Fenza, Maria, Pavone, Vincenzo
Format: Artigo
Sprog:Inglês
Udgivet: The Author(s). Published by Elsevier Ltd. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299864/
https://ncbi.nlm.nih.gov/pubmed/32562843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2020.06.013
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