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IMMUNOHISTOCHEMISTRY OF THE HUMAN ADRENAL CYP11B2 IN NORMAL INDIVIDUALS AND IN PATIENTS WITH PRIMARY ALDOSTERONISM

The CYP11B2 enzyme is the terminal enzyme in the biosynthesis of aldosterone. Immunohistochemistry using antibodies against CYP11B2 defines cells of the adrenal ZG that synthesize aldosterone. CYP11B2 expression is normally stimulated by angiotensin II, but becomes autonomous in primary hyperaldoste...

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Publicado en:Horm Metab Res
Main Authors: Gomez-Sanchez, Celso E., Gomez-Sanchez, Elise P., Nishimoto, Koshiro
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299743/
https://ncbi.nlm.nih.gov/pubmed/32289837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/a-1139-2079
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