Immunohistochemistry of aldosterone synthase leads the way to the pathogenesis of primary aldosteronism

Our group previously purified human and rat aldosterone synthase (CYP11B2 and Cyp11b2, respectively) from their adrenals and verified that it is distinct from steroid 11β-hydroxylase (CYP11B1 or Cyp11b1), the cortisol- or corticosterone-synthesizing enzyme. We now describe their distributions immuno...

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Detalhes bibliográficos
Publicado no:Mol Cell Endocrinol
Main Authors: Nishimoto, Koshiro, Koga, Minae, Seki, Tsugio, Oki, Kenji, Gomez-Sanchez, Elise P., Gomez-Sanchez, Celso E., Naruse, Mitsuhide, Sakaguchi, Tomokazu, Morita, Shinya, Kosaka, Takeo, Oya, Mototsugu, Ogishima, Tadashi, Yasuda, Masanori, Suematsu, Makoto, Kabe, Yasuaki, Omura, Masao, Nishikawa, Tetsuo, Mukai, Kuniaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470036/
https://ncbi.nlm.nih.gov/pubmed/27751767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2016.10.014
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