Immunohistochemistry of aldosterone synthase leads the way to the pathogenesis of primary aldosteronism

Our group previously purified human and rat aldosterone synthase (CYP11B2 and Cyp11b2, respectively) from their adrenals and verified that it is distinct from steroid 11β-hydroxylase (CYP11B1 or Cyp11b1), the cortisol- or corticosterone-synthesizing enzyme. We now describe their distributions immuno...

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發表在:Mol Cell Endocrinol
Main Authors: Nishimoto, Koshiro, Koga, Minae, Seki, Tsugio, Oki, Kenji, Gomez-Sanchez, Elise P., Gomez-Sanchez, Celso E., Naruse, Mitsuhide, Sakaguchi, Tomokazu, Morita, Shinya, Kosaka, Takeo, Oya, Mototsugu, Ogishima, Tadashi, Yasuda, Masanori, Suematsu, Makoto, Kabe, Yasuaki, Omura, Masao, Nishikawa, Tetsuo, Mukai, Kuniaki
格式: Artigo
語言:Inglês
出版: 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470036/
https://ncbi.nlm.nih.gov/pubmed/27751767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2016.10.014
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