Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies

Antibodies targeting the spike protein of SARS-CoV-2 present a promising approach to combat the COVID19 pandemic; however, concerns remain that mutations can yield antibody resistance. We investigate the development of resistance against four antibodies to the spike protein that potently neutralize...

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Publicado no:Science
Main Authors: Baum, Alina, Fulton, Benjamin O., Wloga, Elzbieta, Copin, Richard, Pascal, Kristen E., Russo, Vincenzo, Giordano, Stephanie, Lanza, Kathryn, Negron, Nicole, Ni, Min, Wei, Yi, Atwal, Gurinder S., Murphy, Andrew J., Stahl, Neil, Yancopoulos, George D., Kyratsous, Christos A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299283/
https://ncbi.nlm.nih.gov/pubmed/32540904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abd0831
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