Loading...

FXR1 is a novel MRE11-binding partner and participates in oxidative stress responses

Ataxia-telangiectasia (AT) and MRE11-defective Ataxia-telangiectasia-like disorder (ATLD) patients show progressive cerebellar ataxia. ATM, mutated in AT, can be activated in response to oxidative stress as well as DNA damage, which could be linked to disease-related neurodegeneration. However, the...

Full description

Saved in:
Bibliographic Details
Published in:J Radiat Res
Main Authors: Qi, Fei, Meng, Qingmei, Hayashi, Ikue, Kobayashi, Junya
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299265/
https://ncbi.nlm.nih.gov/pubmed/32211858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rraa011
Tags: Add Tag
No Tags, Be the first to tag this record!