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FXR1 is a novel MRE11-binding partner and participates in oxidative stress responses

Ataxia-telangiectasia (AT) and MRE11-defective Ataxia-telangiectasia-like disorder (ATLD) patients show progressive cerebellar ataxia. ATM, mutated in AT, can be activated in response to oxidative stress as well as DNA damage, which could be linked to disease-related neurodegeneration. However, the...

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Detalhes bibliográficos
Publicado no:J Radiat Res
Main Authors: Qi, Fei, Meng, Qingmei, Hayashi, Ikue, Kobayashi, Junya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299265/
https://ncbi.nlm.nih.gov/pubmed/32211858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rraa011
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