Anti-Ferroptosis Drug Enhances Total-Body Irradiation Mitigation by Drugs that Block Apoptosis and Necroptosis

Mitigation of total-body irradiation (TBI) in C57BL/6 mice by two drugs, which target apoptosis and necroptosis respectively, increases survival compared to one drug alone. Here we investigated whether the biomarker (signature)-directed addition of a third anti-ferroptosis drug further mitigated TBI...

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Detalhes bibliográficos
Publicado no:Radiat Res
Main Authors: Thermozier, Stephanie, Hou, Wen, Zhang, Xichen, Shields, Donna, Fisher, Renee, Bayir, Hulya, Kagan, Valerian, Yu, Jian, Liu, Bing, Bahar, Ivet, Epperly, Michael W., Wipf, Peter, Wang, Hong, Huq, M. Saiful, Greenberger, Joel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299160/
https://ncbi.nlm.nih.gov/pubmed/32134361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR15486.1
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