Coevolution of residues provides evidence of a functional heterodimer of 5-HT(2A)R and 5-HT(2C)R involving both intracellular and extracellular domains

Serotonin is a neurotransmitter that plays a role in regulating activities such as sleep, appetite, mood and substance abuse disorders; serotonin receptors 5-HT(2A)R and 5-HT(2C)R are active within pathways associated with substance abuse. It has been suggested that 5-HT(2A)R and 5-HT(2C)R may form...

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Pubblicato in:Neuroscience
Autori principali: Fongang, Bernard, Cunningham, Kathryn A., Rowicka, Maga, Kudlicki, Andrzej
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299066/
https://ncbi.nlm.nih.gov/pubmed/31158438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2019.05.013
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