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Thrombotic complications of COVID-19 may reflect an upregulation of endothelial tissue factor expression that is contingent on activation of endosomal NADPH oxidase

The high rate of thrombotic complications associated with COVID-19 seems likely to reflect viral infection of vascular endothelial cells, which express the ACE2 protein that enables SARS-CoV-2 to invade cells. Various proinflammatory stimuli can promote thrombosis by inducing luminal endothelial exp...

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Bibliografski detalji
Izdano u:Open Heart
Glavni autori: DiNicolantonio, James J, McCarty, Mark
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7298678/
https://ncbi.nlm.nih.gov/pubmed/32532805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/openhrt-2020-001337
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