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Suppression of NADPH Oxidase Activity May Slow the Expansion of Osteolytic Bone Metastases
Lysophosphatidic acid (LPA), generated in the microenvironment of cancer cells, can drive the proliferation, invasion, and migration of cancer cells by activating G protein-coupled LPA receptors. Moreover, in cancer cells that have metastasized to bone, LPA signaling can promote osteolysis by induci...
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| Опубликовано в: : | Healthcare (Basel) |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5041061/ https://ncbi.nlm.nih.gov/pubmed/27571113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/healthcare4030060 |
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