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Lower brain fatty acid amide hydrolase in treatment-seeking patients with alcohol use disorder: a positron emission tomography study with [C-11]CURB

The endocannabinoid enzyme, fatty acid amide hydrolase (FAAH), has been proposed as a therapeutic target for alcohol use disorder (AUD) and co-morbid psychiatric illnesses. Investigating this target in the living human brain and its relationship to clinical outcome is a critical step of informed dru...

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Veröffentlicht in:Neuropsychopharmacology
Hauptverfasser: Best, Laura M., Williams, Belinda, Le Foll, Bernard, Mansouri, Esmaeil, Bazinet, Richard P., Lin, Lin, De Luca, Vincenzo, Lagzdins, Dina, Rusjan, Pablo, Tyndale, Rachel F., Wilson, Alan A., Hendershot, Christian S., Heilig, Markus, Houle, Sylvain, Tong, Junchao, Kish, Stephen J., Boileau, Isabelle
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7298050/
https://ncbi.nlm.nih.gov/pubmed/31910433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-0606-2
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