K(V)11.1 Potassium Channel and the Na(+)/H(+) Antiporter NHE1 Modulate Adhesion-Dependent Intracellular pH in Colorectal Cancer Cells

Increasing evidence indicates that ion channels and transporters cooperate in regulating different aspects of tumor pathophysiology. In cancer cells, H(+)/HCO(3)(-) transporters usually invert the transmembrane pH gradient typically observed in non-neoplastic cells, which is thought to contribute to...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Iorio, Jessica, Duranti, Claudia, Lottini, Tiziano, Lastraioli, Elena, Bagni, Giacomo, Becchetti, Andrea, Arcangeli, Annarosa
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297984/
https://ncbi.nlm.nih.gov/pubmed/32587517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00848
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