Dual-Targeting Nanoparticle-Mediated Gene Therapy Strategy for Hepatocellular Carcinoma by Delivering Small Interfering RNA

As a gene therapy strategy, RNA interference (RNAi) offers tremendous tumor therapy potential. However, its therapeutic efficacy is restricted by its inferior ability for targeted delivery and cellular uptake of small interfering RNA (siRNA). This study sought to develop a dual-ligand nanoparticle (...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Zheng, Qi Chang, Jiang, Shuai, Wu, Yu Zhe, Shang, Dan, Zhang, Yong, Hu, Shao Bo, Cheng, Xiang, Zhang, Chen, Sun, Ping, Gao, Yang, Song, Zi Fang, Li, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297947/
https://ncbi.nlm.nih.gov/pubmed/32587849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00512
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