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Non-Viral Nanoparticle Delivers Small Interfering RNA to Macrophages In Vitro and In Vivo

Macrophages are increasingly being viewed as therapeutic target for various cancers and many inflammatory diseases. Sequence specific gene reduction by siRNA represents an attractive approach to modulate macrophage function. However, delivery of the therapeutic siRNA into macrophages by non-viral na...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhang, Mei, Gao, Yunxiang, Caja, Kevin, Zhao, Bocheng, Kim, Julian A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370462/
https://ncbi.nlm.nih.gov/pubmed/25799489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118472
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