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Non-Viral Nanoparticle Delivers Small Interfering RNA to Macrophages In Vitro and In Vivo

Macrophages are increasingly being viewed as therapeutic target for various cancers and many inflammatory diseases. Sequence specific gene reduction by siRNA represents an attractive approach to modulate macrophage function. However, delivery of the therapeutic siRNA into macrophages by non-viral na...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Zhang, Mei, Gao, Yunxiang, Caja, Kevin, Zhao, Bocheng, Kim, Julian A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370462/
https://ncbi.nlm.nih.gov/pubmed/25799489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118472
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