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CU06-1004 (endothelial dysfunction blocker) ameliorates astrocyte end-feet swelling by stabilizing endothelial cell junctions in cerebral ischemia/reperfusion injury

ABSTRACT: Cerebral ischemia, or stroke, is widespread leading cause of death and disability. Surgical and pharmacological interventions that recover blood flow are the most effective treatment strategies for stroke patients. However, restoring the blood supply is accompanied by severe reperfusion in...

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Detalhes bibliográficos
Publicado no:J Mol Med (Berl)
Main Authors: Kim, Dong Young, Zhang, Haiying, Park, Songyi, Kim, Yeaji, Bae, Cho-Rong, Kim, Young-Myeong, Kwon, Young-Guen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297708/
https://ncbi.nlm.nih.gov/pubmed/32415357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01920-z
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