Sac-1004, a vascular leakage blocker, reduces cerebral ischemia—reperfusion injury by suppressing blood–brain barrier disruption and inflammation

BACKGROUND: Blood–brain barrier (BBB) breakdown and inflammation are critical events in ischemic stroke, contributing to aggravated brain damage. The BBB mainly consists of microvascular endothelial cells sealed by tight junctions to protect the brain from blood-borne substances. Thus, the maintenan...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Neuroinflammation
मुख्य लेखकों: Zhang, Haiying, Park, Joon Ha, Maharjan, Sony, Park, Jeong Ae, Choi, Kyu-Sung, Park, Hyojin, Jeong, Yoonjeong, Ahn, Ji Hyeon, Kim, In Hye, Lee, Jae-Chul, Cho, Jeong Hwi, Lee, In-Kyu, Lee, Choong Hyun, Hwang, In Koo, Kim, Young-Myeong, Suh, Young-Ger, Won, Moo-Ho, Kwon, Young-Guen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2017
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481915/
https://ncbi.nlm.nih.gov/pubmed/28645333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0897-3
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