Hepatitis C virus exploits cyclophilin A to evade PKR

Counteracting innate immunity is essential for successful viral replication. Host cyclophilins (Cyps) have been implicated in viral evasion of host antiviral responses, although the mechanisms are still unclear. Here, we show that hepatitis C virus (HCV) co-opts the host protein CypA to aid evasion...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Colpitts, Che C, Ridewood, Sophie, Schneiderman, Bethany, Warne, Justin, Tabata, Keisuke, Ng, Caitlin F, Bartenschlager, Ralf, Selwood, David L, Towers, Greg J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2020
Onderwerpen:
Immunology and Inflammation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297535/
https://ncbi.nlm.nih.gov/pubmed/32539931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52237
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