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Hepatitis C virus exploits cyclophilin A to evade PKR

Counteracting innate immunity is essential for successful viral replication. Host cyclophilins (Cyps) have been implicated in viral evasion of host antiviral responses, although the mechanisms are still unclear. Here, we show that hepatitis C virus (HCV) co-opts the host protein CypA to aid evasion...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Colpitts, Che C, Ridewood, Sophie, Schneiderman, Bethany, Warne, Justin, Tabata, Keisuke, Ng, Caitlin F, Bartenschlager, Ralf, Selwood, David L, Towers, Greg J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297535/
https://ncbi.nlm.nih.gov/pubmed/32539931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52237
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