In vivo modeling of metastatic human high-grade serous ovarian cancer in mice

Metastasis is responsible for 90% of human cancer mortality, yet it remains a challenge to model human cancer metastasis in vivo. Here we describe mouse models of high-grade serous ovarian cancer, also known as high-grade serous carcinoma (HGSC), the most common and deadliest human ovarian cancer ty...

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Publicado en:PLoS Genet
Main Authors: Kim, Olga, Park, Eun Young, Klinkebiel, David L., Pack, Svetlana D., Shin, Yong-Hyun, Abdullaev, Zied, Emerson, Robert E., Coffey, Donna M., Kwon, Sun Young, Creighton, Chad J., Kwon, Sanghoon, Chang, Edmund C., Chiang, Theodore, Yatsenko, Alexander N., Chien, Jeremy, Cheon, Dong-Joo, Yang-Hartwich, Yang, Nakshatri, Harikrishna, Nephew, Kenneth P., Behringer, Richard R., Fernández, Facundo M., Cho, Chi-Heum, Vanderhyden, Barbara, Drapkin, Ronny, Bast, Robert C., Miller, Kathy D., Karpf, Adam R., Kim, Jaeyeon
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297383/
https://ncbi.nlm.nih.gov/pubmed/32497036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008808
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