Variants in the CHRNA5–CHRNA3–CHRNB4 Region of Chromosome 15 Predict Gastrointestinal Adverse Events in the Transdisciplinary Tobacco Use Research Center Smoking Cessation Trial

INTRODUCTION: Reducing adverse events from pharmacologic treatment is an important goal of precision medicine and identifying genetic predictors of adverse events is a step toward this goal. In 2012, King et al. reported associations between genetic variants and adverse events in a placebo-controlle...

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Publicat a:Nicotine Tob Res
Autors principals: Culverhouse, Robert C, Chen, Li-Shiun, Saccone, Nancy L, Ma, Yinjiao, Piper, Megan E, Baker, Timothy B, Bierut, Laura J
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Original Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297092/
https://ncbi.nlm.nih.gov/pubmed/30882151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntz044
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