Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy

In the U.S.A., cocaine is the second most abused illicit drug. Variants within the CHRNB3-A6 gene cluster have been associated with cigarette consumption in several GWAS. These receptors represent intriguing candidates for the study of cocaine dependence because nicotinic receptors are thought to be...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Sadler, Brooke, Haller, Gabe, Agrawal, Arpana, Culverhouse, Rob, Bucholz, Kathleen, Brooks, Andy, Tischfield, Jay, Johnson, Eric O., Edenberg, Howard, Schuckit, Marc, Saccone, Nancy, Bierut, Laura, Goate, Alison
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894386/
https://ncbi.nlm.nih.gov/pubmed/24675634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04497
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