DHX33 Recruits Gadd45a To Cause DNA Demethylation and Regulates a Subset of Gene Transcription

RNA helicase DHX33 was found to regulate the transcription of multiple genes involved in cancer development. But the underlying molecular mechanism remains unclear. Here, we found DHX33 associated extensively with gene promoters at CG-rich region. Its deficiency reduced the loading of active RNA pol...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Feng, Weimin, Chen, Shiyun, Wang, Jiuling, Wang, Xingshun, Chen, Huaiyong, Ning, Wen, Zhang, Yandong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296211/
https://ncbi.nlm.nih.gov/pubmed/32312884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00460-19
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