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Interferon Alpha Favors Macrophage Infection by Visceral Leishmania Species Through Upregulation of Sialoadhesin Expression

Type I interferons (IFNs) induced by an endogenous Leishmania RNA virus or exogenous viral infections have been shown to exacerbate infections with New World Cutaneous Leishmania parasites, however, the impact of type I IFNs in visceral Leishmania infections and implicated mechanisms remain to be un...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Van Bockstal, Lieselotte, Bulté, Dimitri, Van den Kerkhof, Magali, Dirkx, Laura, Mabille, Dorien, Hendrickx, Sarah, Delputte, Peter, Maes, Louis, Caljon, Guy
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296180/
https://ncbi.nlm.nih.gov/pubmed/32582193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01113
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