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Impact of clinically acquired miltefosine resistance by Leishmania infantum on mouse and sand fly infection

OBJECTIVES: This study evaluated the implications of clinically acquired miltefosine resistance (MIL-R) by assessing virulence in mice and sand flies to reveal the potential of MIL-R strains to circulate. METHODS: Experimental infections with the MIL-R clinical Leishmania infantum isolate MHOM/FR/20...

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Detalhes bibliográficos
Publicado no:Int J Parasitol Drugs Drug Resist
Main Authors: Van Bockstal, Lieselotte, Bulté, Dimitri, Hendrickx, Sarah, Sadlova, Jovana, Volf, Petr, Maes, Louis, Caljon, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215113/
https://ncbi.nlm.nih.gov/pubmed/32388220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2020.04.004
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