Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion

Demyelination in vascular dementia (VD) is partly attributable to inflammation induced by chronic cerebral hypoperfusion (CCH). Remyelination contributes to the recovery of cognitive impairment by inducing the proliferation and differentiation of oligodendrocyte progenitor cells. It was previously r...

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Veröffentlicht in:Front Aging Neurosci
Hauptverfasser: Li, Meixi, Meng, Nan, Guo, Xin, Niu, Xiaoli, Zhao, Zhongmin, Wang, Wei, Xie, Xiaohua, Lv, Peiyuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296049/
https://ncbi.nlm.nih.gov/pubmed/32581761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.00137
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