Transcriptional repression of Myc underlies the tumour suppressor function of AGO1 in Drosophila

Here, we report novel tumour suppressor activity for the Drosophila Argonaute family RNA-binding protein AGO1, a component of the miRNA-dependent RNA-induced silencing complex (RISC). The mechanism for growth inhibition does not, however, involve canonical roles as part of the RISC; rather, AGO1 con...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Development
Autors principals: Zaytseva, Olga, Mitchell, Naomi C., Guo, Linna, Marshall, Owen J., Parsons, Linda M., Hannan, Ross D., Levens, David L., Quinn, Leonie M.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295588/
https://ncbi.nlm.nih.gov/pubmed/32527935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.190231
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars