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Transcriptional repression of Myc underlies the tumour suppressor function of AGO1 in Drosophila
Here, we report novel tumour suppressor activity for the Drosophila Argonaute family RNA-binding protein AGO1, a component of the miRNA-dependent RNA-induced silencing complex (RISC). The mechanism for growth inhibition does not, however, involve canonical roles as part of the RISC; rather, AGO1 con...
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| 出版年: | Development |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists Ltd
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7295588/ https://ncbi.nlm.nih.gov/pubmed/32527935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.190231 |
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