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The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy

Erastin was initially discovered as a small molecule compound that selectively kills tumor cells expressing ST and RAS(V12) and was later widely investigated as an inducer of ferroptosis. Ferroptosis is a recently discovered form of cell death caused by peroxidation induced by the accumulation of in...

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Bibliographische Detailangaben
Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Zhao, Yuechen, Li, Yanqing, Zhang, Ruifeng, Wang, Feng, Wang, Tiejun, Jiao, Yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295539/
https://ncbi.nlm.nih.gov/pubmed/32606760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S254995
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