IL-15 superagonist RLI has potent immunostimulatory properties on NK cells: implications for antimetastatic treatment

BACKGROUND: As the immune system is compromised in patients with cancer, therapeutic strategies to stimulate immunity appear promising, to avoid relapse and increase long-term overall survival. Interleukin-15 (IL-15) has similar properties to IL-2, but does not cause activation-induced cell death no...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Desbois, Mélanie, Béal, Coralie, Charrier, Mélinda, Besse, Benjamin, Meurice, Guillaume, Cagnard, Nicolas, Jacques, Yannick, Béchard, David, Cassard, Lydie, Chaput, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Clinical/Translational Cancer Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295443/
https://ncbi.nlm.nih.gov/pubmed/32532840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000632
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