Stromal LAG-3(+) cells infiltration defines poor prognosis subtype muscle-invasive bladder cancer with immunoevasive contexture

BACKGROUND: Lymphocyte activation gene 3 (LAG-3) is a promising immune checkpoint therapeutic target being evaluated in clinical trials. We assessed the LAG-3(+) cells distribution, its association with clinical outcomes and immune contexture and its role in the landscape of muscle-invasive bladder...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Immunother Cancer
Päätekijät: Zeng, Han, Zhou, Quan, Wang, Zewei, Zhang, Hongyu, Liu, Zhaopei, Huang, Qiuren, Wang, Jiajun, Chang, Yuan, Bai, Qi, Xia, Yu, Wang, Yiwei, Xu, Le, Dai, Bo, Guo, Jianming, Liu, Li, Zhu, Yu, Xu, Jiejie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMJ Publishing Group 2020
Aiheet:
Immunotherapy Biomarkers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295439/
https://ncbi.nlm.nih.gov/pubmed/32540859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000651
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