Comparing serum protein levels can aid in differentiating HPV-negative and -positive oropharyngeal squamous cell carcinoma patients

BACKGROUND: The surrogate immunohistochemical marker, p16(INK4a), is used in clinical practice to determine the high-risk human papillomavirus (HPV) status of oropharyngeal squamous cell carcinomas (OPSCC). With a specificity of 83%, this will misclassify some patients compared with direct HPV testi...

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Pubblicato in:PLoS One
Autori principali: Dickinson, Amy, Saraswat, Mayank, Syrjänen, Stina, Tohmola, Tiialotta, Silén, Robert, Randén-Brady, Reija, Carpén, Timo, Hagström, Jaana, Haglund, Caj, Mattila, Petri, Mäkitie, Antti, Joenväärä, Sakari, Silén, Suvi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295232/
https://ncbi.nlm.nih.gov/pubmed/32542012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233974
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