High levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) in the serum are associated with poor prognosis in HPV-negative squamous cell oropharyngeal cancer

BACKGROUND: An emerging subset of oropharyngeal squamous cell carcinomas (OPSCC) is caused by HPV. HPV-positive OPSCC has a better prognosis than HPV-negative OPSCC, but other prognostic markers for these two different diseases are scarce. Our aim was to evaluate serum levels and tumor expression of...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Carpén, Timo, Sorsa, Timo, Jouhi, Lauri, Tervahartiala, Taina, Haglund, Caj, Syrjänen, Stina, Tarkkanen, Jussi, Mohamed, Hesham, Mäkitie, Antti, Hagström, Jaana, Mattila, Petri S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682571/
https://ncbi.nlm.nih.gov/pubmed/31240326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02362-4
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