Zwitterionic-to-cationic charge conversion polyprodrug nanomedicine for enhanced drug delivery

Zwitterionic surface modification is a promising strategy for nanomedicines to achieve prolonged circulation time and thus effective tumor accumulation. However, zwitterion modified nanoparticles suffer from reduced cellular internalization efficiency. Methods: A polyprodrug-based nanomedicine with...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Wang, Sheng, Zhang, Fuwu, Yu, Guocan, Wang, Zhantong, Jacobson, Orit, Ma, Ying, Tian, Rui, Deng, Hongzhang, Yang, Weijing, Chen, Zhi-Yi, Chen, Xiaoyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295052/
https://ncbi.nlm.nih.gov/pubmed/32550894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.47849
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