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Aggregation pathways of human γ D crystallin induced by metal ions revealed by time dependent methods

Cataract formation is a slow accumulative process due to protein aggregates promoted by different factors over time. Zinc and copper ions have been reported to induce the formation of aggregates opaque to light in the human gamma D crystallin (HγD) in a concentration and temperature dependent manner...

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Foilsithe in:PeerJ
Main Authors: Fernández-Silva, Arline, French-Pacheco, Leidys, Rivillas-Acevedo, Lina, Amero, Carlos
Formáid: Artigo
Teanga:Inglês
Foilsithe: PeerJ Inc. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295030/
https://ncbi.nlm.nih.gov/pubmed/32566392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.9178
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