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A Bayesian Null Interval Hypothesis Test Controls False-Discovery Rates and Improves Sensitivity in Label-Free Quantitative Proteomics

Statistical significance tests are a common feature in quantitative proteomics workflows. The Student’s t-test is widely used to compute the statistical significance of a protein’s change between two groups of samples. However, the t-test’s null hypothesis asserts that the difference in means betwee...

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書目詳細資料
發表在:J Proteome Res
Main Authors: Millikin, Robert J., Shortreed, Michael R., Scalf, Mark, Smith, Lloyd M.
格式: Artigo
語言:Inglês
出版: 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294927/
https://ncbi.nlm.nih.gov/pubmed/32243168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.9b00796
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