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Stable isotope labeling and label-free proteomics of Drosophila parkin null mutants

Parkinson’s disease (PD) is characterized by loss of dopaminergic neurons in the substantia nigra and formation of intracytoplasmic Lewy bodies (LBs). Loss-of-function mutations in parkin which encodes an E3 ubiqutin protein ligase contribute to a predominant cause of a familial form of PD termed au...

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Detalhes bibliográficos
Main Authors: Xun, Zhiyin, Kaufman, Thomas C., Clemmer, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766925/
https://ncbi.nlm.nih.gov/pubmed/19705877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr9006238
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