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Structure Optimization of Gatastatin for the Development of γ-Tubulin-Specific Inhibitor
[Image: see text] Gatastatin (O(7)-benzyl glaziovianin A) is a γ-tubulin-specific inhibitor that is used to investigate γ-tubulin function in cells. We have previously reported that the unsubstituted phenyl ring of the O(7)-benzyl group in gatastatin is important for γ-tubulin inhibition. To obtain...
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| Publicado no: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2020
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7294552/ https://ncbi.nlm.nih.gov/pubmed/32550991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00526 |
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