Transplanted senescent renal scattered tubular-like cells induce injury in the mouse kidney

Cellular senescence, a permanent arrest of cell proliferation, is characterized by a senescence-associated secretory phenotype (SASP), which reinforces senescence and exerts noxious effects on adjacent cells. Recent studies have suggested that transplanting small numbers of senescent cells suffices...

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Veröffentlicht in:Am J Physiol Renal Physiol
Hauptverfasser: Kim, Seo Rin, Jiang, Kai, Ferguson, Christopher M., Tang, Hui, Chen, Xiaojun, Zhu, XiangYang, Hickson, LaTonya J., Tchkonia, Tamara, Kirkland, James L., Lerman, Lilach O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294341/
https://ncbi.nlm.nih.gov/pubmed/32223312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00535.2019
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