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Dual blockade of protease-activated receptor 1 and 2 additively ameliorates diabetic kidney disease
Protease-activated receptors (PARs) are coagulation protease targets, and they increase expression of inflammatory cytokines and chemokines in various diseases. Of all PARs, previous reports have shown that PAR1 or PAR2 inhibition is protective against diabetic glomerular injury. However, how PAR1 a...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7294339/ https://ncbi.nlm.nih.gov/pubmed/32200667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00595.2019 |
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