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Myeloid cell-derived coagulation tissue factor is associated with renal tubular damage in mice fed an adenine diet

Patients with chronic kidney disease (CKD) commonly exhibit hypercoagulability. Increased levels of uremic toxins cause thrombogenicity by increasing tissue factor (TF) expression and activating the extrinsic coagulation cascade. TF is induced in monocytes and macrophages under pathological conditio...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Yamakage, Shu, Oe, Yuji, Sato, Emiko, Okamoto, Koji, Sekimoto, Akiyo, Kumakura, Satoshi, Sato, Hiroshi, Yoshida, Mai, Nagasawa, Tasuku, Miyazaki, Mariko, Ito, Sadayoshi, Mackman, Nigel, Takahashi, Nobuyuki
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190319/
https://ncbi.nlm.nih.gov/pubmed/34108522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91586-5
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