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TRPV1 activation stimulates NKCC1 and increases hydrostatic pressure in the mouse lens

The porcine lens response to a hyperosmotic stimulus involves an increase in the activity of an ion cotransporter sodium-potassium/two-chloride cotransporter 1 (NKCC1). Recent studies with agonists and antagonists pointed to a mechanism that appears to depend on activation of transient receptor pote...

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Bibliographic Details
Published in:Am J Physiol Cell Physiol
Main Authors: Shahidullah, Mohammad, Mandal, Amritlal, Mathias, Richard T., Gao, Junyuan, Križaj, David, Redmon, Sarah, Delamere, Nicholas A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294325/
https://ncbi.nlm.nih.gov/pubmed/32293931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00391.2019
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